PML Polyclonal Antibody
產品名稱： PML Polyclonal Antibody
英文名稱： PML Polyclonal Antibody
產品編號： K002372P
產品價格： null
產品產地： 北京市通州區馬駒橋聯
品牌商標： solarbio
更新時間： 2025-11-13T16:50:54
使用范圍：
北京索萊寶科技有限公司
- 聯系人 : 索萊寶-龔思雨
- 地址 : 北京市北京經濟技術開發區環科中路16號26幢3層301
- 郵編 :
- 所在區域 : 北京
- 電話 : 181****6239 點擊查看
- 傳真 : 點擊查看
- 郵箱 : 3193328036@qq.com
- 二維碼 : 點擊查看
Anti-PML Polyclonal Antibody
品牌：solarbio | 貨號：K002372P
| 英文名稱 | Anti-PML Polyclonal Antibody |
|---|---|
| 別名 | MYL;PP8675;RNF71;TRIM19 |
| 應用 | WB IHC IF |
| 稀釋比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反應 | Human Mouse |
| 蛋白分子量 | 98kDa |
| Gene ID | 5371 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human PML |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human PML |
| Subcellular Locations | Cytoplasm Cytoplasmic side Early endosome membrane Endoplasmic reticulum membrane Nucleus PML body Peripheral membrane protein nucleolus nucleoplasm |
| Swiss Prot | P29590 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. |