鐵蛋白Fe65樣蛋白2抗體
產(chǎn)品名稱： 鐵蛋白Fe65樣蛋白2抗體
英文名稱： APBB3
產(chǎn)品編號： bs-11637R
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標： BIOSS
更新時間： 2025-08-18T10:57:58
使用范圍： WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,
北京索萊寶科技有限公司
- 聯(lián)系人 : 索萊寶-龔思雨
- 地址 : 北京市北京經(jīng)濟技術(shù)開發(fā)區(qū)環(huán)科中路16號26幢3層301
- 郵編 :
- 所在區(qū)域 : 北京
- 電話 : 181****6239 點擊查看
- 傳真 : 點擊查看
- 郵箱 : 3193328036@qq.com
- 二維碼 : 點擊查看
Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.