肌營養(yǎng)不良蛋白相關(guān)蛋白1抗體
產(chǎn)品名稱： 肌營養(yǎng)不良蛋白相關(guān)蛋白1抗體
英文名稱： Utrophin
產(chǎn)品編號： bs-11394R
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標：
更新時間： 2025-08-18T10:57:58
使用范圍： ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,
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Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.